Table 1 Patient characteristics.
Patient characteristics | R-CHOP vs. R-CHOP + 2 R | (R-)CHOP vs. Burkitt protocol* | CHOP* | Total cohort |
|---|---|---|---|---|
n | 397 | 59 | 27 | 483 |
Age [years] | 58 (14.2) | 59.1 (13.4) | 49.5 (18.1) | 57.8 (14.5) |
Histological subtype | ||||
DLBCL | 312 (78.6%) | 35 (59.3%) | 1 (3.7%) | 348 (72.0%) |
Other large B-cell | 38 (9.6%) | 9 (15.3%) | 1 (3.7%) | 48 (9.9%) |
Lymphoma | ||||
Follicular lymphoma | 21 (5.3%) | 4 (6.8%) | 0 (0%) | 25 (5.2%) |
T-cell lymphoma | 2 (0.5%) | 10 (16.9%) | 25 (96.2%) | 37 (7.7%) |
IPI risk group | ||||
Low | 158 (39.8%) | 14 (23.7%) | 13 (48.1%) | 185 (38.3%) |
Low-intermediate | 103 (25.9%) | 16 (27.1%) | 6 (22.2%) | 125 (25.9%) |
High-intermediate | 85 (21.4%) | 16 (27.1%) | 4 (14.8%) | 105 (21.7%) |
High | 51 (12.8%) | 13 (22.0%) | 4 (14.8%) | 68 (14.1%) |
IPI parameters | ||||
Age > 60 | 202 (50.9%) | 33 (55.9%) | 18 (66.7%) | 244 (50.5%) |
Stage III or IV | 223 (56.2%) | 44 (74.6%) | 17 (63.0%) | 284 (58.8%) |
Elevated LDH | 218 (54.9%) | 40 (67.8%) | 11 (40.7%) | 269 (55.7%) |
ECOG > 1 | 35 (8.8%) | 9 (15.3%) | 3 (11.1%) | 47 (9.7%) |
Extranodal site >1 | 109 (27.5%) | 19 (32.2%) | 7 (25.9%) | 135 (28.0%) |
Interim Deauville score >2 | 279 (70.3%) | 55 (93.2%) | 20 (74.1%) | 354 (73.3%) |
