Fig. 1: Mutational landscape of HCLc.
From: The genomic landscape and clonal evolutionary trajectory of classical hairy cell leukemia
From top to bottom: Driver coding somatic SNVs; noncoding somatic SNVs prioritized by the scoring algorithms CADD (C), REMM (R), FATHMM-MKL (FA) and FunSeq2 (F2); CNA events and structural variants (translocations) with driver function; kataegis and mutational signatures identified in 10 HCLc tumors. In the first two panels, the scale bars indicate the total number of coding and noncoding SNVs identified in each gene in our cohort of HCLc samples.
