Fig. 1: UBTF-TDs in adult AML. | Leukemia

Fig. 1: UBTF-TDs in adult AML.

From: UBTF tandem duplications define a distinct subtype of adult de novo acute myeloid leukemia

Fig. 1

A Fragment analysis of mutant (665 bp) and wild-type (617 bp) alleles of UBTF in a patient with a 48-bp tandem duplication. B Integrative Genomics Viewer (IGV) visualization showing the soft-clipped reads and increased coverage in UBTF exon 13. C UBTF gene structure and location of UBTF-TDs. The common minimal duplicated motif in exon 13 is highlighted in red.

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