Fig. 6: Imaging Findings in CNS BPDCN.

Axial MRI of the face of a teenage male with BPDCN shows diffusely enlarged lacrimal glands (arrows in A), diffusely enlarged parotid glands (arrows in B), and a diffusely enlarged adenoid (arrowhead in B). CT of the neck, chest, abdomen, and pelvis reveals multicompartmental lymphadenopathy (involving the cervical, axillary, hilar, mediastinal, periportal, retroperitoneal, and iliac chain and inguinal lymph nodes) and hepatosplenomegaly (not shown). Brain and spine MRI reveal no leptomeningeal disease. Periorbital ecchymosis (“raccoon eyes”) at presentation in a patient later diagnosed with BPDCN (C).