Table 2 Univariable and multivariable Cox regression, factors impacting on molecular event-free survival.

Age

1.03

1.00–1.06

0.02

1.03

1.00–1.06

0.06

MRD marker^a

0.45

0.14–1.52

0.20

FLT3-ITD at diagnosis

0.93

0.22–3.94

0.92

Previous midostaurin

1.47

0.65–3.35

0.35

On midostaurin at time of molecular failure

2.39

1.05–5.46

0.04

2.23

0.74–6.74

0.20

Previous allo-SCT

0.36

0.14–0.97

0.04

0.85

0.27–2.63

0.80

Molecular failure type^b

2.15

0.93–4.94

0.07

1.28

0.51–3.22

0.60

Time between diagnosis and molecular failure

0.93

0.86–1.00

0.05

0.98

0.89–1.07

0.60

qPCR copy number at molecular failure (per 100 increase)

1.74

1.14–2.64

0.01

1.84

1.10–3.07

0.02