Fig. 1: Illustration of type and localization of mutations affecting the bZIP region of the CEBPA gene. | Leukemia

Fig. 1: Illustration of type and localization of mutations affecting the bZIP region of the CEBPA gene.

From: Prognostic impact of CEBPA mutational subgroups in adult AML

Fig. 1

Mutations in the bZIP region (AA272-358) are typically in-frame insertion or deletion mutations (bZIPInDel), whereas frameshift insertions/deletions or nonsense mutations causing a premature translational termination (bZIPSTOP), and single base-pair missense mutations (bZIPms) are less common.

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