Table 2 Summaries of the PICOG model derived on the training study population.

From: Enhanced Risk Stratification for Children and Young Adults with B-Cell Acute Lymphoblastic Leukemia: A Children’s Oncology Group Report

Variable

Type

Coefficient

HR (95% CI)

P-value

τ(D29 ΜRD)

Continuous

−0.102

0.90 (0.89–0.92)

<0.001

τ(D8 ΜRD)

Continuous

−0.040

0.96 (0.94–0.98)

<0.001

FRG

Binary

−0.741

0.48 (0.41–0.56)

<0.001

URG

Binary

0.644

1.91 (1.59–2.29)

<0.001

WBClog

Continuous

0.156

1.17 (1.12–1.22)

<0.001

CNS Status

Categorical

   

(Ref = CNS1)

CNS2

0.386

1.47 (1.24–1.74)

<0.001

 

CNS3

0.364

1.44 (0.88–2.37)

0.151

Age Dx

Continuous

0.061

1.06 (1.05–1.07)

<0.001

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