Table 4 5-year relapse-free survival probability estimates (SE) for subgroups by COG retrospective and COG Prognostic Index risk classifications in the combined training/testing data.

From: Enhanced Risk Stratification for Children and Young Adults with B-Cell Acute Lymphoblastic Leukemia: A Children’s Oncology Group Report

 

COG PI Classification

COG Risk Classification

Low

Standard

Intermediate

High

SR Fav

0.970 (0.003)

0.927 (0.015)

--

--

SR Avg

0.960 (0.008)

0.937 (0.005)

0.904 (0.018)

--

SR High

0.924 (0.052)a

0.899 (0.012)

0.831 (0.013)

0.732 (0.022)

HR Fav

0.982 (0.009)

0.964 (0.014)

--

--

HR

0.955 (0.014)

0.903 (0.010)

0.850 (0.010)

0.660 (0.015)

VHR

--

--

--

0.534 (0.044)

  1. Empty cells indicate insufficient sample size for reliable estimation (<25 patients).
  2. Patients in SR-Fav/Avg are missing MRD8, as such they are not represented in this table.
  3. aLarge standard error reflects small sample size (n = 28) and hence broader uncertainty about the RFS estimate.