Fig. 3: DNA methylation of tumor suppressor genes in BPDCN, AML, and CMML. | Leukemia

Fig. 3: DNA methylation of tumor suppressor genes in BPDCN, AML, and CMML.

From: Genome-wide DNA methylation-analysis of blastic plasmacytoid dendritic cell neoplasm identifies distinct molecular features

Fig. 3

a Average promoter DNA methylation (beta values) of tumor suppressor genes in BPDCN, AML, and CMML. b Average gene body DNA methylation (beta values) of tumor suppressor genes in BPDCN, AML, and CMML. c Average promoter and gene body DNA methylation in selected tumor suppressor genes (for a complete representation of significantly divergent TSGs see Supplementary Fig. 2). Differences between BPDCN and the AML/CMML were assessed by unpaired Wilcoxon test and significant levels are indicated by asterisks (*p < 0.05, **p < 0.01, and ***p < 0.001).

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