Table 3 Analysis of extramedullary involvement in a univariate and multivariate analysis, taking into account CD2/CD25 expression patterns in MC, age at inclusion and sex.

From: Prognostic impact of expression of CD2, CD25, and/or CD30 in/on mast cells in systemic mastocytosis: a registry study of the European Competence Network on Mastocytosis

 

Univariate analysis OR

Univariate analysis p value

Multivariate analysis OR

Multivariate analysis p value

Intercept

–

–

−13.1

<0.01

CD2 negative MC

2.52

<0.01

2.63

<0.01

CD25 positive MC

1.1

0.28

1.3

0.34

Age at inclusion

1.05

<0.01

1.05

<0.01

Male sex

2.19

<0.01

1.72

<0.01

  1. The OR of extramedullary involvement was analyzed with logistic regression analysis taking into account CD2 expression, CD25 expression, age at inclusion and sex.
  2. In the multivariate analysis, there is a 2.63 higher OR for extramedullary involvement in SM patients with CD2-negative MC compared to SM patients with CD2-positive MC.
  3. OR odds ratio, MC mast cells, SM systemic mastocytosis.
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