Table 1 Baseline characteristics of patient cohorts included in model development and analysis.

From: Prediction of resistance to hydroxyurea therapy in patients with polycythemia vera: a machine learning study (PV-AIM) validated in a prospective interventional phase IV trial (HU-F-AIM)

 

HU-RES (N = 733)

NON-RES (N = 571)

Overall (N = 1304)

Gender, n (%)

 Female

307 (41.9)

328 (57.4)

635 (48.7)

 Male

426 (58.1)

243 (42.6)

669 (51.3)

Age at index (years), mean (SD)

68.4 (11.2)

71.2 (10.8)

69.6 (11.1)

History of TE, n (%)

 Yes

107 (14.6)

93 (16.3)

200 (15.3)

 No

626 (85.4)

478 (83.7)

1104 (84.7)

Number of phlebotomies (annualized), mean (SD)

0.74 (1.44)

0.28 (0.77)

0.54 (1.22)

ANC (×109/L), mean (SD)

9.58 (6.00)

8.36 (5.58)

9.05 (5.85)

HCT (%), mean (SD)

49.0 (7.40)

47.2 (7.37)

48.2 (7.43)

HGB (g/dl), mean (SD)

15.6 (2.61)

15.4 (2.49)

15.5 (2.56)

NLR, mean (SD)

6.72 (6.37)

6.06 (5.83)

6.43 (6.15)

RDW (%), mean (SD)

18.1 (3.22)

17.1 (3.05)

177 (3.18)

WBC (×109/L), mean (SD)

13.1 (9.02)

11.1 (6.36)

12.3 (8.03)