Table 2 Risk stratification of monoclonal gammopathy of undetermined significance (MGUS).
From: Current risk stratification and staging of multiple myeloma and related clonal plasma cell disorders
IMWG Risk Category | Relative Risk of Progression | Absolute Risk of Progression at 20 years (%) | Absolute Risk of Progression at 20 years, accounting for death as a competing risk (%) |
|---|---|---|---|
Low risk • M-protein <1.5 g/dL • normal sFLCR (0.26-1.65) • IgG isotype | 1 | 5 | 2 |
Low-intermediate risk (any 1 factor being abnormal) | 5.4 | 21 | 10 |
High-Intermediate Risk (any 2 factors abnormal) | 10.1 | 37 | 18 |
High-risk (all three factors abnormal) | 20.8 | 58 | 27 |
