Fig. 3: Prognostic impact of additional mutations.
From: A molecular signature predicts hematologic evolution in polycythemia vera patients
A Forest plots summarizing the individual impact of each genomic category for overall survival (left panel) and hematologic transformation (right panel). High risk mutations include SRSF2, EZH2, IDH1, IDH2, CBL and NFE2 mutations. CNV include abnormalities of chromosomes 1q, 5, 7, 8, 13 and 20. Significant associations are represented in blue. B Kaplan-Meier curves showing the impact of allele burden on overall survival for TET2 (left panel) and DNMT3A (right panel) mutations.
