Fig. 4: A genomic classification for predicting survival and transformation.
From: A molecular signature predicts hematologic evolution in polycythemia vera patients
A Sequential definition of the three genomic groups. B Kaplan-Meier curves showing the impact of the genomic groups on overall survival (left panel) and hematologic transformation (right panel). C Results of the multistate model considering the transitions between chronic phase, hematologic transformations and death. The following variables at diagnosis were included: genomic groups, age, gender, history of thrombosis, leukocytes and platelets counts, neutrophil/lymphocyte ratio and constitutional symptoms. A stepwise downward selection was performed. PV polycythemia vera.
