Table 3 Mutations identified in LP tumor cells in HRD-related genes.

From: Genetic lesions in nodular lymphocyte-predominant Hodgkin lymphoma and T cell/histiocyte-rich large B-cell lymphoma identified by whole genome sequencing

Gene

Case 1

Case 3

Case 4

Case 5

Case 6

ATM

    

p.Ser1250Tyr *

BARD1

 

p.Asp172His *

p.Ser186Gly *

  

BLM

 

p.Leu1042TrpfsTer2 +

   

BRCA1

   

p.Asp1546Asn *

p.Lys1207Asn *

BRCA2

p.Asp381Tyr *

   

p.Ala1648Thr *

BRIP1

 

p.Met425Val *

  

p.Val894Ala, p.Arg162Ter #

NBN

 

p.Gln448Ter #

  

p.Glu383Ter #

RAD50

    

p.Glu1033Ter #

  1. Mutation consequence is indicated : * missense mutation, # stop-gain, + frameshift. In cases 2 and 7, no mutations in homologous repair deficiency (HRD)-related genes were observed.
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