Fig. 4: Predictive performance of the three models and ELTS score.

Receiver-operating characteristic (ROC) curves to compare the predictive performance of the three models and ELTS score in the whole cohort and in the first-line imatinib and first-line 2G-TKI groups. Time-dependent AUC values for therapy failure at 1 (A, D, G), 3 (B, E, H), and 5 years (C, F, I) using data from the French CML Observatory. No significant difference was detected with the omnibus Gray test (p is indicated in each graph).