Table 3 Quality of Life (measured with the EORTC QLQ C30) in comparison to general population norms.
From: Quality of life and life satisfaction in long-term survivors of acute myeloid leukemia
N | Raw score, mean (SD) | Relevant impairment (z <-1) N (%) | z-scores compared to age- and sex-matched reference cohorts, mean (95%CI) | P valueb | |
|---|---|---|---|---|---|
Overall Score | |||||
Global health status (EORTC QLQ C30) | 426 | 70.6 (22.64) | 50 (11.74) | 0.26 (0.16 to 0.35) | <0.0001 |
Functioning Scales | |||||
Social functioning | 420 | 71.98 (32.82) | 132 (31.34) | –0.52 (–0.65 to –0.40) | <0.0001 |
Cognitive functioning | 424 | 77.12 (26.32) | 125 (29.48) | –0.47 (–0.61 to –0.34) | <0.0001 |
Emotional functioning | 425 | 70.10 (26.17) | 110 (25.88) | –0.25 (–0.36 to –0.14) | 0.003 |
Role functioning | 419 | 72.04 (31.44) | 103 (24.58) | --0.24 (–0.35 to –0.13) | 0.058 |
Physical functioning | 426 | 79.81 (21.21) | 69 (16.20) | –0.02 (–0.11 to 0.08) | 0.054 |
Symptom Scales | |||||
Financial difficulties | 423 | 20.17 (32.17) | 110 (26.00) | –0.44 (–0.57 to –0.30) | 0.012 |
Constipation | 425 | 8.78 (21.26) | 70 (16.47) | –0.02 (–0.12 to 0.08)a | <0.0001 |
Diarrhea | 426 | 11.58 (21.61) | 71 (16.67) | –0.15 (–0.26 to –0.04)a | 0.052 |
Appetite Loss | 425 | 8.31 (19.66) | 63 (14.82) | 0.01 (–0.08 to 0.10)a | <0.0001 |
Insomnia | 424 | 34.67 (33.07) | 92 (21.70) | –0.12 (–0.22 to –0.03) | 0.026 |
Dyspnea | 423 | 27.27 (32.25) | 109 (25.77) | –0.21 (–0.32 to –0.10) | 0.226 |
Pain | 431 | 25.49 (30.31) | 56 (13.30) | 0.16 (0.06 to 0.25) | <0.0001 |
Nausea/Vomiting | 424 | 4.36 (12.50) | 38 (8.96) | –0.03 (–0.13 to 0.08)a | <0.0001 |
Fatigue | 417 | 32.25 (26.91) | 96 (23.02) | –0.14 (–0.24 to –0.05) | 0.043 |
