Fig. 2: Results from the enrichment analysis of the differentially methylated positions (DMPs) using EWAS toolkit. | Leukemia

Fig. 2: Results from the enrichment analysis of the differentially methylated positions (DMPs) using EWAS toolkit.

From: Unraveling the molecular landscape of Erdheim–Chester disease: new insights from methylome and transcriptome integration

Fig. 2

A Results of the Gene Ontology (GO) enrichment analysis of DMPs. Most relevant terms are displayed in the plot. The colours of the bars represent the different groups in which the GO terms were classified. B Scatter plot displaying significant transcription factors (TFs). X-axis exhibits percentage of DMPs overlapping transcription factor binding sites for each TF. Y-axis represents this value divided by percentage of all analysed CpGs overlapping with the same TF. The colour denotes the transcription factor’s family, while the size reflects the significance level in terms of log10(p-value).

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