Fig. 5: Comparison of cytomorphology between chronic myeloid leukemia (CML) patients.
From: Granulocyte abundance and maturation state at diagnosis predicts treatment-free remission in CML
The analysis included four CML patient groups: patients maintaining treatment-free remission (TFR) at 36 months, patients with a late (> 6, ≤ 36 months) or early relapse (≤ 6 months) following tyrosine kinase inhibitor (TKI) discontinuation and patients failing to respond to TKI during the first year after diagnosis according to European LeukemiaNet 2020 criteria. Box plots with individual data points for each cytomorphological variable, categorized by patient groups, with P-values shown (Wilcoxon rank-sum test). The black dashed line connects the groups by their medians. Abbreviations: σ Standard deviation, Mdn Median. M:E Ratio, Myeloid to erythroid ratio where myeloid cells included promyelocytes, myelocytes, metamyelocytes, neutrophils, eosinophils, basophils, promonocytes, and monocytes. Erythroid cells included proerythroblasts and erythroblasts.
