Table 1 Summary of clinical and pathological features of 82 patients with monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) or enteropathy-associated T-cell lymphoma (EATL).

Reported celiac disease

0/52 (0%)

13/30 (43%)

<0.005

Age, median, years (range)

67 (29-91)

64 (34-86)

0.37

Gender (male/female)

27:25

19:11

0.2

Acute event at presentation

38/44 (86%)

12/18 (67%)

0.09

    Bowel perforation

33/44 (75%)

8/18 (44%)

0.037

    Bowel obstruction

12/44 (27%)

6/18 (33%)

0.76

    Stage I/II

27/44 (61%)

8/13 (61%)

1.000

    Stage III/IV

17/44 (39%)

5/13 (39%)

0-1

18/40 (45%)

4/8 (50%)

1.000

≥2

22/40 (55%)

4/8 (50%)

    Typical

31/52 (60%)

    Atypical

21/52 (40%)

Pleomorphic

13/52 (25%)

30/30 (100%)

<0.005

Anaplastic

1/52 (2%)

15/30 (50%)

<0.005

Necrosis

7/52 (13%)

22/30 (73%)

<0.005

Starry-sky

5/52 (10%)

3/30 (10%)

1.000

Angiotropism

14/51 (27%)

19/29 (65%)

<0.005

Epitheliotropism

36/41 (88%)

2/20 (10%)

<0.005

Moderate/abundant inflammation

3/52 (6%)

20/30 (67%)

    CD8

47/52 (90%)

4/30 (13%)

<0.005

    CD56

46/52 (88%)

2/28 (7%)

<0.005

    CD3

52/52 (100%)

27/30 (90%)

0.046

    CD2

20/47 (42%)

12/24 (50%)

0.619

    CD5

2/51 (4%)

2/30 (7%)

0.624

    CD7

48/48 (100%)

22/23 (96%)

0.324

    CD4

2/52 (4%)

2/27 (7%)

0.603

    CD103

40/51 (78%)

15/25 (60%)

0.108

    CD30

0/47 (0%)

25/29 (86%)

<0.005

    TIA1

47/52 (90%)

20/25 (80%)

0.108

    Granzyme B

37/52 (71%)

19/28 (68%)

0.596

    Perforin

27/52 (52%)

22/29 (76%)

<0.005

    CD20

9/49 (18%)

1/29 (3%)

0.046

    CD79a

3/41 (7%)

0/10 (0%)

0.567

    TCRβ

17/50 (34%)

8/28 (29%)

0.472

    TCRγδ

26/50 (52%)

8/27 (30%)

0.050

    TCRαβ-TCRγδ + 

22/49 (44%)

4/26 (15%)

0.012

    TCRαβ + TCRγδ-

12/49 (24%)

4/26 (15%)

0.391

    TCRαβ + TCRγδ + 

4/49 (8%)

3/26 (11%)

0.685

    TCRαβ-TCRγδ-

11/49 (22%)

15/26 (58%)

0.004