Fig. 1: I Association of echocardiographic and cardiac biomarkers with survival outcomes after Cilta-cel. | Leukemia

Fig. 1: I Association of echocardiographic and cardiac biomarkers with survival outcomes after Cilta-cel.

From: MyCARdiac score: integrating cardiac imaging and biomarkers to predict outcomes in RRMM patients receiving cilta-cel

Fig. 1

Univariate Cox regression analyses of echocardiographic parameters and cardiac biomarkers with respect to progression-free survival (PFS, a) and overall survival (OS, b). Hazard ratios with 95% confidence intervals (95% CI) are shown. Raw p-values and false discovery rate (FDR)-adjusted p-values are reported, with statistical significance indicated by asterisks based on the adjusted p-values (p ≤ 0.05, p < 0.01). c–g Kaplan–Meier curves of PFS stratified by optimized cut-off values for LVPWd, LVM-Index, LVEF, CAC, and NT-proBNP. h–l Kaplan–Meier curves of OS stratified by the same parameters. HR, 95% CI, and log-rank p-values are shown, and numbers at risk are indicated below each plot. m–q Box plots showing the associations of the same parameters with the occurrence of adverse cardiac events. The Mann–Whitney U test was used for statistical analysis, and statistical significance was defined as p < 0.05.

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