Table 1 Clinical and laboratory variables at baseline of the University of Florence cohort.
Clinical and laboratory variables at baseline | ET patients (n = 100; 50%) | PrePMF patients (n = 100; 50%) | P-values |
|---|---|---|---|
Age in year; median (range) | 62 (25-92) | 64 (18–86) | 0.4 |
Sex, females; n (%) | 63 (63) | 51 (51) | 0.09 |
White blood cells x 109/L; median (range) | 8 (4.4–16.5) | 9.1 (4.1–36) | < 0.01 |
Hemoglobin, g/dL; median (range) | 14.4 (9.9–15.9) | 13.7 (9–15.6) | 0.01 |
Hematocrit, %; median (range) | 43 (35–50) | 41.5 (32–50) | 0.01 |
Platelets, x109/L; median (range) | 624 (452–2000) | 640 (220–1660) | 0.1 |
Lactate dehydrogenase, U/L; median (range) | 220 (150–403) | 283 (157–727) | < 0.01 |
Palpable splenomegaly; n (%) | 14 (14) | 38 (38) | < 0.01 |
Driver mutations | Â | ||
JAK2; n (%) | 76 | 74 | 0.6 |
CALR type 1/1 like; n (%) | 9 | 13 | |
CALR type 2/2 like; n (%) | 5 | 4 | |
MPL; n (%) | 5 | 7 | |
Triple negative; n (%) | 5 | 2 | |
