Fig. 7: Pearson correlations show significant correlations between the SHG-derived structural data and the passive elastic parameters, as well as a higher degree of myofibrillar disorder with the sarcomere length in stretched single EDL fibers. | Light: Science & Applications

Fig. 7: Pearson correlations show significant correlations between the SHG-derived structural data and the passive elastic parameters, as well as a higher degree of myofibrillar disorder with the sarcomere length in stretched single EDL fibers.

From: Optical prediction of single muscle fiber force production using a combined biomechatronics and second harmonic generation imaging approach

Fig. 7

Both structural parameters, the CAS (a) and the stretch-corrected VD (b), obtained in relaxed (pCa 9) wt (gray) and mdx (red) single fibers show significant correlations with the sarcomere lengths. In particular, the higher the stretch was (SL↑), the less ordered the myofibrillar arrangement became (CAS↓, VD↑). Similarly, the myofibrillar disarray, i.e., the low CAS (c) and large VD values (d), significantly correlated with increased maximum stress values that occurred during stretching

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