Fig. 4
From: 3D cellular-resolution imaging in arteries using few-mode interferometry
a–c IVOCT, IVFMI, and histology images showing a cross-section of the cadaveric coronary artery with smooth muscle cells residing within a collagen network. The smooth muscle cells could not be clearly visualised in the standard IVOCT image, while IVFMI showed smooth muscle cells (low-intensity, slit-like structures indicated by blue arrows in the inset of (b)) that are consistent in size and shape with the smooth muscle cells seen in the corresponding histology (green arrow in the inset of (c)). d IVFMI image of a cross-section of an artery that shows probable smooth muscle cells (red arrows in the inset) and macrophages undergoing diapedesis (green arrows in the inset). e IVFMI image of a cross-section of a cadaver coronary artery showing probable thrombus, with cells that are consistent with leucocytes embedded in the intraluminal mass. A Gaussian blur filter with a radius of 2 μm was applied to the cross-sectional IVFMI images. Scale bars are 100 μm for all images.
