Fig. 4: BP-based PTT alone relieves the immunosuppressive tumour microenvironment. | Light: Science & Applications

Fig. 4: BP-based PTT alone relieves the immunosuppressive tumour microenvironment.

From: Black phosphorus-based photothermal therapy with aCD47-mediated immune checkpoint blockade for enhanced cancer immunotherapy

Fig. 4

a IR thermal images of A20 tumour-bearing mice in groups that received two laser irradiation (808 nm, 1 W cm−2) treatments for BP and PBS exposure. b Temperature change with time at the tumour sites in the BP and PBS groups under 808-nm laser irradiation for 10 min. c Representative flow cytometry plot (left) and quantification of murine CD11b+ cells on CD45+ cells (right). d Representative flow cytometry plot (left) and quantification of CD8+ T cells on CD3+ T cells (right). Data are presented as the mean ± s.e.m. (n = 3). The statistical significance was calculated via the two-tailed Student’s t test. The asterisk indicates a statistically significant difference (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.001)

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