Fig. 2: Imaging for tissue phantom. | Light: Science & Applications

Fig. 2: Imaging for tissue phantom.

From: Transmissive-detected laser speckle contrast imaging for blood flow monitoring in thick tissue: from Monte Carlo simulation to experimental demonstration

Fig. 2

a Schematic diagram of tissue phantom experimental devices. The experiments consisted of two parts: 1. The total thickness was constant, and the blood flow signals at /from different depths were measured (left); 2. The position of the blood flow signal was constant, and the thickness of the layer above the signal was changed (right). b Blood flow maps of part 1 captured with conventional LSCI and TR-LSCI (The dashed lines represent the inner wall of the capillary glass tube). The scale line represents the distance to the surface of the intralipid. The blood was pumped to flow in the capillary glass tube at a constant speed of 4 mm s−1. c Quantitative analysis of effect of the depth of the capillary on background subtracted signal intensity. Data are expressed in (mean ± standard error), n = 3. d SBR of two imaging modes in the Monte Carlo simulation according to the corresponding settings in (c). Here, SBR was defined as the proportion of light emanating from the signal layer to the total light emanating from each layer. e Blood flow maps of part 2 captured with conventional LSCI and TR-LSCI (The dashed lines represent the inner wall of the capillary glass tube). The pump pushes the blood to flow in the capillary glass tube at a constant speed of 4 mm s−1. f Quantitative analysis of effect of the thickness of the intralipid on background subtracted signal intensity. Data are expressed in (mean ± standard error), n = 3. g SBR of two imaging modes in the Monte Carlo simulation according to the corresponding settings in (e). Here, the SBR was defined as the proportion of light emanating from the signal layer to the total light emanating from each layer

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