Fig. 3: UFF-PAM of brain hemodynamics under hypoxia. | Light: Science & Applications

Fig. 3: UFF-PAM of brain hemodynamics under hypoxia.

From: Real-time whole-brain imaging of hemodynamics and oxygenation at micro-vessel resolution with ultrafast wide-field photoacoustic microscopy

Fig. 3

a–c sO2 images of the entire mouse cortex under a cycle of normoxia, hypoxia, and then returned to normoxia. d–f Close-up images of the dashed box regions in (a–c). g The averaged sO2 changes in arteries (sO2_a) and veins (sO2_v). The gray areas indicate the hypoxia challenges. The arrows represent the time points corresponding to (a–c). h The diameter changes of the marked artery and vein in (d). i Vessel area (VA) change of the whole cortex. N = 4. The data in (g–i) are shown as mean ± s.e.m. Scale bar, 1 mm in (a–c), 100 μm in (d–f)

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