Fig. 4: UFF-PAM of brain hemodynamics in response to SNP. | Light: Science & Applications

Fig. 4: UFF-PAM of brain hemodynamics in response to SNP.

From: Real-time whole-brain imaging of hemodynamics and oxygenation at micro-vessel resolution with ultrafast wide-field photoacoustic microscopy

Fig. 4

a–d sO2 images of the entire cortex of the mouse brain at baseline, as well as 2.5, 5.5, and 20 min after SNP injection. e–h Close-up sO2 images at the respective time points, as indicated by the white dotted box in (a). The yellow arrows point to the representative dilated vessels, and the white arrows point to the representative constricted microvessels. i The average diameter changes of arteries and veins. The grey area represents the duration of SNP injection. j Vessel area change of the whole cortex. k The average sO2 change of arteries and veins. The arrows in (i–k) represent the time points corresponding to (a–d). N = 3. The data in (i–k) are shown as mean ± s.e.m. Scale bar, 1 mm for (a–d), and 100 μm for (e–h)

Back to article page