Fig. 5: Therapeutic effect of Au@CDs and SERS monitoring of the catalytic reaction in the TME.

a Treatment schedule for in vivo anti-metastasis study. b Tumor volume and c tumor weight in mice after Au@CDs + H2O2 + 808 nm laser treatments (2 W cm−2) with different concentration of Au@CDs. d Illustration of Raman studies of intratumor oxidative stress processes. e Time-dependent SERS spectra during the process of oxidative stress in tumor and f time-dependent intensities of the characteristic bands of oxTMB.