Fig. 8: A simulation from the physics-informed forward model.
From: DEEP-squared: deep learning powered De-scattering with Excitation Patterning
a1–2 The xy and xz views of the excitation PSF. b1–2 The xy and xz views of the emission PSF. c1 Illustration of the light scattering process in a scattering tissue used to model the scattering point spread function (sPSF). c2 The scattering point spread function at a two-scattering-length depth. c3 The scattering point spread function at a seven-scattering-length depth. d1 A synthetic beads object (the maximum intensity projection over the z-axis). d2 The simulated DEEP-TFM image of the object in (d1) 7 scattering lengths below the surface (before detection on the camera). Note that the maximum photon count in the image is close to 5 photons. d3 The simulated DEEP-TFM image in (d2) detected on the simulated EMCCD camera. The scale bars in (a2), (b2), (c2), and (c3) are 5 μm. The scale bar in (d3) is 20 μm
