Fig. 1: Neural activity modulation with chemical delivery.

Neural activity modulation with chemical delivery. a Schematic of a multifunctional neural probe with integrated microfluidic chips. Reproduced with permission from ref. ²⁵. Copyright 2015, The Royal Society of Chemistry. b A wireless fluidic probe driven by Joule heating-induced polymer expansion. Reproduced with permission from ref. ³³. Copyright 2015, Cell press. c Surface coating for sustained drug release. Reproduced with permission from ref. ³⁶. Copyright 2019, John Wiley and Sons. d Electrodes with dexamethasone/PEDOT:PSS hybrid nanotubes and drug release with electrical stimulation. Reproduced with permission from ref. ³⁸. Copyright 2006, John Wiley and Sons. e Schematic and structure of an organic electronic ion pump-based delivery/sensing neural interface. Reproduced with permission from ref. ⁴¹. Copyright 2016, National Academy of Sciences