Fig. 4: Examples of optical modulation/recording interfaces with optical fibers and microLEDs. | Microsystems & Nanoengineering

Fig. 4: Examples of optical modulation/recording interfaces with optical fibers and microLEDs.

From: Recent developments in multifunctional neural probes for simultaneous neural recording and modulation

Fig. 4

a A microwire electrode bundle surrounded by four optical fibers for optical neural modulation of freely behaving mice. Reproduced with permission from ref. 19. Copyright 2012, Nature Publishing Group. b A transparent ZnO microprobe array for optogenetic neural manipulation. Reproduced with permission from ref. 77. Copyright 2015, Nature Publishing Group. c A soft alginate-PAAm hydrogel optical fiber with low Young’s modulus and reduced inflammatory response of the brain tissue. Reproduced with permission from ref. 79. Copyright 2018, John Wiley and Sons. d A multilayer, injectable optical modulation/recording interface based on µ-ILEDs for optical neural modulation. Reproduced with permission from ref. 80. Copyright 2013, AAAS

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