Fig. 2: Simulation of electrical impedance and cell deformation.
From: Single-cell electro-mechanical shear flow deformability cytometry
a Side view (z-x) of the vertical and lateral electric field for an applied voltage of ±1 V. with a solid dielectric sphere and ellipsoid. Colour scale is the magnitude of the electric field (V/m). b The two sets of electrodes create an impedance signal consisting of two sets of antisymmetric bimodal Gaussians. c Sensitivity plots for vertical impedance Z1 and (d) lateral impedance Z2 as a function of the deformation index (major/minor axis) for three different sizes of particles. e Electrical deformability (Z1/Z2) as a function of the deformation index for three different sizes of particles. Particles were modelled as homogenous solid dielectric objects with specific conductivity and permittivity (εp = 2.5ε0 and σp = 2.7 × 10−3 S/m) and a frequency of 500 kHz. Simulated channel dimensions are 200μm long, 28 μm high and 40 μm wide
