Fig. 2
From: Inflammatory and infectious manifestations of immunodeficiency in the gastrointestinal tract
Upper endoscopy performed on a 2-year-old child with failure to thrive revealed granulomata in the duodenal submucosa a. Specimens from the jejunum showed shortened villi without increased inflammation b. Distal colon biopsy samples lacked granulomas, but revealed Paneth cell metaplasia c and pigmented macrophages (arrows, d). Analysis of peripheral blood revealed impaired oxidative burst, confirming the diagnosis of chronic granulomatous disease. (Hematoxylin and eosin; original magnification: × 400 a, c; × 200 b; × 600 d)
