Fig. 5
From: Inflammatory and infectious manifestations of immunodeficiency in the gastrointestinal tract
Cytomegalovirus infection causes erosion and ulceration of the colonic mucosa. Viral inclusions are present in inflamed granulation tissue. The associated crypts contain apoptotic bodies and karyorrhectic debris a. Nuclear inclusions (arrow) are large and amphophilic, whereas cytoplasmic inclusions are bright red and granular (block arrow). Epithelial cells that harbor adenovirus inclusions appear disordered (right) at low power compared with those lining a normal villus (left). Inclusions (arrow) are amphophilic and replace the entire nucleus. (Hematoxylin and eosin; original magnification: × 400 a, c; × 600 b, d)
