Table 3 2SC, FH, and additional immunohistochemistries performed in FH-deficient renal cell carcinomas

From: Pattern multiplicity and fumarate hydratase (FH)/S-(2-succino)-cysteine (2SC) staining but not eosinophilic nucleoli with perinucleolar halos differentiate hereditary leiomyomatosis and renal cell carcinoma-associated renal cell carcinomas from kidney tumors without FH gene alteration

Cases

2SC

FH

Vimentin

CD10

P504S

CK7

CA9

TFE3

1

      

2

+

+

+

  

3

+

 

+ (Low)

 

4

+

+

 

5

+

      

6

+

      

7

+

 

+

    

8

+

 

+

+

  

9

+

+

  

+

 

10

+ (Focal)

  

+ (Low)

  

11

+

      

12

+

      

13

+

 

+

  

14

+

      

15

+

  

+

16

+

      

17

+

+

      

18

+

 

+

+ (Heterogenous)

 

19

+

++

 

+ (Low)

+

20

+

      

21

+

+

+

+ (Low)

22

+

      

23

+

 

 

  

24

+

+

  
  1. NA not available