Fig. 3

HER2 gene status in urothelial carcinoma. Red probe indicates HER2 and green probe indicates chromosome 17 centromere. a Negative HER2 FISH assay (×400). b Amplified/positive HER2 FISH assay with clusters of HER2 gene signals (×400). c Polysomy for HER2 (×400). FISH fluorescent in situ hybridization, HER2 human epidermal growth factor receptor 2