Table 3 Univariate and multivariate analyses of clinicopathological features for prognosis of study group invasive micropapillary carcinoma

From: Precise pathologic diagnosis and individualized treatment improve the outcomes of invasive micropapillary carcinoma of the breast: a 12-year prospective clinical study

Factor

 

Univariate

  

Multivariate

 
 

HR

95 % CI

p value

HR

95 % CI

p value

DFS

 Tumor size

2.573

1.797–3.684

<0.001

1.665

1.122–2.470

0.011

 LNM

5.692

2.630–12.318

<0.001

3.224

1.125–8.593

0.018

 LVI

5.264

3.217–8.614

<0.001

2.737

1.531–4.895

0.001

 Histologic grade

2.231

1.623–3.066

<0.001

1.183

0.818–1.712

0.372

 ER

0.235

0.156–0.353

<0.001

0.299

0.174–0.516

<0.001

 PR

0.405

0.269–0.609

<0.001

0.907

0.538–1.531

0.715

 HER-2

1.248

1.031–1.511

0.021

1.023

0.836–1.251

0.826

 IMPC composition

1.084

0.931–1.264

0.299

—

—

—

OS

 Tumor size

2.384

1.618–3.511

<0.001

1.443

0.933–2.199

0.100

 LNM

8.112

2.973–22.140

<0.001

6.219

1.456–26.563

0.014

 LVI

5.005

2.909–8.611

<0.001

2.688

1.420–5.090

0.002

 Histologic grade

2.121

1.506–2.988

<0.001

1.219

0.813–1.828

0.338

 ER

0.286

0.184–0.445

<0.001

0.448

0.246–0.816

0.009

 PR

0.422

0.272–0.656

<0.001

0.773

0.428–1.397

0.394

 HER-2

1.274

1.041–1.559

0.019

1.071

0.869–1.321

0.519

 IMPC composition

1.006

0.853–1.186

0.942

—

—

—

  1. HR hazard ratio, 95% CI 95% confidence interval, LNM lymph node metastasis, LVI lymphovascular invasion, ER estrogen receptor, PR progesterone receptor, HER-2 human epidermal growth factor receptor 2, DFS disease-free survival, OS overall survival
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