Fig. 2
Summary of the comprehensive characterization of 57 hydatidiform mole tissues from 25 patients with no recessive pathogenic variants in NLRP7 or KHDC3L. Recapitulation of the characterization of the referred hydatidiform mole tissues with the various results obtained by morphological analysis, flow cytometry, karyotype analysis, and fluorescent in situ hybridization, p57KIP2 immunohistochemistry, microsatellite genotyping, and the conclusion of the analyses. Unrelated patients are numbered from 1 to 25, and only one of them has a half-sister with recurrent hydatidiform moles. The number of analyzed tissues for each patient is provided under the “Histopathology” column. More than one tissue of the same type are indicated by their numbers; lack of a number indicates one such tissue or item. In the other columns, results on the different tissues are listed by their chronological order. POC stands for product of conception; NM, for non-molar; MC, miscarriage; CHM, complete hydatidiform mole; PHM, partial hydatidiform mole; n.a., indicates result not available and is used to indicate an inconclusive result or not available samples; Dip, diploid; Bip, biparental; Dis, dispermic; Tri, triploid.
