Fig. 1
From: Prognostic significance of tumor-infiltrating lymphocytes in ductal carcinoma in situ of the breast
Parameters of TILs assessment. a Touching lymphocytes (x40) defined by lymphocytes that touch the basement membrane (BM) or are located within one lymphocyte cell thickness distance from basement membrane (yellow arrows); inset closer view for touching TILs, b TILs assessment within 0.2, 0.5, and 1.0 mm distance from the involved ducts, and c evaluation of hotspots (largest number of lymphoid cells aggregates within the lesion as shown in area surrounded by black dashed circle)
