Table 2 Summary of copy number variations identified in adrenocortical carcinoma histological variants
Genes (locus) analyzed | Conventional (n = 38) | Myxoid (n = 7) | Oncocytic (n = 17) | ||||
|---|---|---|---|---|---|---|---|
Loss | Gain | Loss | Gain | Loss | Gain | ||
RB1/13q12 | (13q14.2) | 18 (47%) | / | 2 (28%) | / | 1 (6%) | / |
CDKN2A/CEN9 | (9p21.3) | 15 (39%) | / | 2 (28/%) | / | 1 (6%) | / |
ZNRF3/22q13 | (22q12.1) | 13 (34%) | / | 1 (14%) | / | / | / |
TERT/5q31 | (5p15.33) | / | 16 (42%) | / | 3 (43%) | / | 4 (23%) |
CDK4/CEN12 | (12q14.1) | / | 14 (37%) | / | 6 (86%) | / | 2 (12%) |
