Fig. 4 | Modern Pathology

Fig. 4

From: Solid papillary carcinoma with reverse polarity of the breast harbors specific morphologic, immunohistochemical and molecular profile in comparison with other benign or malignant papillary lesions of the breast: a comparative study of 9 additional cases

Fig. 4

a Higher power view showing that solid papillary carcinoma with reverse polarity consists of numerous papillae closely packekd with cuboid to colomnar neoplastic cells. b Higher magnification focusing on one papillary structure. Tumor cells own cytoplasm which is located near the basal layer and near the fibrovascular cores, whereas the nucleus is located at the opposite side, giving the impression of reverse polarity (hematoxylin–eosin–saffron)

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