Fig. 4 | Modern Pathology

Fig. 4

From: Refinement of high-risk endometrial cancer classification using DNA damage response biomarkers: a TransPORTEC initiative

Fig. 4

T-cell immune infiltrates (CD8+) (a) and PD-1 expression (b) across our refined high-risk endometrial cancer five molecular subgroups: (1) POLE mutated (POLE), (2) microsatellite instable (MSI), (3) no specific molecular profile/-H2AX positive (NSMP -H2AX-), (4) TP53 mutated/Non Homologous End-Joining negative (P53 NHEJ-), (5) no specific molecular profile/-H2AX positive (NSMP -H2AX+), and (6) TP53 mutated/Non Homologous End-Joining positive (P53 NHEJ+). #: Out of range data were excluded for graphical representation (NCD8 = 7, NPD-1 = 1 tumors), but were included for statistical analysis (Mann Whitney test: p-value *p < 0.05; **p < 0.01)

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