Table 4 Clinicopathologic features of the derivation cohort
Characteristics | Frozen section | |||
|---|---|---|---|---|
Total (n = 436) | Adenocarcinoma in situ (n = 290) | Minimally invasive adenocarcinoma (n = 146) | P value | |
Age | ||||
≤60 | 291 (67) | 217 (75) | 74 (51) | < 0.001 |
>60 | 145 (33) | 73 (25) | 72 (49) | |
Sex | ||||
Male | 137 (31) | 84 (29) | 53 (36) | 0.127 |
Female | 299 (69) | 206 (71) | 93 (64) | |
Smoking | ||||
Yes | 31 (7) | 18 (6) | 13 (9) | 0.301 |
No | 405 (93) | 272 (94) | 133 (91) | |
Tumor size (cm) | ||||
<1 | 301 (69) | 234 (81) | 67 (46) | < 0.001 |
1–1.4 | 101 (23) | 44 (15) | 57 (39) | |
≥1.5 | 34 (8) | 12 (4) | 22 (15) | |
Subpleural | ||||
Yes | 108 (25) | 69 (24) | 39 (27) | 0.505 |
No | 328 (75) | 221 (76) | 107 (73) | |
Consolidation/Tumor ratio | ||||
>0.25 | 98 (22) | 50 (17) | 48 (33) | < 0.001 |
≤0.25 | 338 (78) | 240 (83) | 98 (67) | |
Location | ||||
Upper | 281 (64) | 183 (63) | 98 (67) | 0.008 |
Middle | 37 (9) | 18 (6) | 19 (13) | |
Lower | 118 (27) | 89 (31) | 29 (20) | |
Carcinoembryonic antigen (μg/L) | ||||
≥5 | 27 (6) | 5 (2) | 22 (15) | < 0.001 |
<5 | 409 (94) | 285 (98) | 124 (85) | |
Final pathology | ||||
Others | 408 (94) | 285 (98) | 123 (84) | < 0.001 |
IA | 28 (6) | 5 (2) | 23 (16) | |
Surgical type | ||||
Lobectomy | 101 (23) | 54 (19) | 47 (32) | 0.003 |
Limited resection | 335 (77) | 236 (81) | 99 (68) | |
