Table 1 Comparison of FoxP3+, CD8+, and CD4+ lymphocytes in autologous stem cell transplant patients, allogeneic stem cell transplant patients, and normal controls with all biopsies included

From: Colonic graft-vs.-host disease in autologous versus allogeneic transplant patients: earlier onset, more apoptosis, and lack of regulatory T-cell attenuation

 

Auto SCT

Allo SCT

Normal

Auto vs. Allo

Auto vs. normal

Allo vs. normal

Mean lymphocytes/HPF (range)

P-value

LPL FoxP3+

9.2 (1–24)

5.3 (0–22)

6.3 (1–14)

0.03

0.22

0.55

LPL CD8+

30.3 (4–78)

23.0 (0–101)

29.5 (12–77)

0.27

0.91

0.32

LPL CD4+

32.6 (8–67)

25.3 (0–83)

34.5 (14–50)

0.14

0.71

0.04

IEL FoxP3+

0.19 (0–1)

0.06 (0–1.3)

0.04 (0–0.5)

0.07

0.12

0.69

IEL CD8+

1.8 (0–5)

4.1 (0–45)

4.0 (0–10)

0.29

0.03

0.95

IEL CD4+

0.24 (0–1)

0.25 (0–2)

0.04 (0–0.5)

0.91

0.06

0.07

  1. Allo, allogeneic; Auto, autologous; HPF, high-power field; IEL, intraepithelial lymphocyte; LPL, lamina propria lymphocytes
  2. Bold values indicate statistically significant P-value
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