Fig. 1 | Modern Pathology

Fig. 1

From: Thioredoxin-interacting protein is an independent risk stratifier for breast ductal carcinoma in situ

Fig. 1

Characterization of TXNIP expression in ductal carcinoma in situ. a Western blot analysis of the anti-TXNIP antibody confirmed a single specific band at 44 kDa in a variety of cell lines, image for MCF-7 shown, b TXNIP cytoplasmic expression in normal breast tissue showing expression in the epithelium and a few scattered myoepithelial cells. Occasional membrane and/or nuclear staining is also seen. TXNIP immunohistochemistry expression in ductal carcinoma in situ showing variable intensities from negative (c), weak (d), moderate (e), and strong (f) staining (×20 magnification). g Full-face section of a ductal carcinoma in situ case mixed with invasive carcinoma and show moderate TXNIP expression in ductal carcinoma in situ but reduced/negative expression in the adjacent invasive carcinoma component

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