Fig. 2

Hierarchical cluster analysis for similarity between superficial and deep nevi from 14 patients. A cluster dendrogram was generated from the hierarchical complete linkage clustering of 14 pairs of superficial nevi (S) and deep nevi (D) samples based on the expression data of 39 miRNA species from each nevus at FDRs of <0.1. The 2 main clusters comprised 1 group populated by 9 exclusively superficial samples (3.S, 2.S, 7.S, 13.S, 8.S, 14.S, 12.S, 5.S, and 11.S), which we assume represent atypical nevi, and the second group populated by the remaining 19 samples (14 deep and 5 superficial nevi), which we assume represent benign nevi