Table 2 Thirty-nine microRNAs (miRNAs) differentially expressed between sun-exposed superficial and deep nevi

From: Detection of a MicroRNA molecular signature of ultraviolet radiation in the superficial regions of melanocytic nevi on sun-exposed skin

miRNA ID

IPA ID of miR family representative (same 7-nt seed sequence)

Unadjusted p-Value

FDR

LOG

hsa-miR-582-5p

 

9.00E−05

0.085

1.32

hsa-miR-181a-3p

hsa-miR-181a-1-3p

1.03E−03

0.087

0.47

hsa-miR-181d-5p

hsa-miR-181a-5p

9.30E−04

0.085

0.45

hsa-miR-106b-5p

hsa-miR-17-5p

7.20E−04

0.085

0.27

hsa-miR-1233-3p

 

9.30E−04

0.085

−0.66

hsa-miR-20b-3p

 

1.68E−03

0.095

−0.72

hsa-miR-6740-3p

 

1.44E−03

0.092

−0.86

hsa-miR-4465

hsa-miR-26a-5p

9.30E−04

0.085

−0.91

hsa-miR-6738-3p

 

1.41E−03

0.092

−0.93

hsa-miR-376b-5p

 

1.72E−03

0.095

−0.94

hsa-miR-3157-5p

 

1.30E−03

0.092

−1.02

hsa-miR-5195-3p

hsa-miR-145-5p

5.10E−04

0.085

−1.03

hsa-miR-4730

 

1.17E−03

0.092

−1.10

hsa-miR-7153-5p

hsa-miR-146a-5p

8.50E−04

0.085

−1.11

hsa-miR-4724-3p

 

1.18E−03

0.092

−1.11

hsa-miR-6841-5p

 

1.71E−03

0.095

−1.11

hsa-miR-944

 

1.49E−03

0.093

−1.12

hsa-miR-182-3p

 

3.60E−04

0.085

−1.12

hsa-miR-92a-2-5p

 

6.70E−04

0.085

−1.13

hsa-miR-489-5p

 

1.57E−03

0.095

−1.14

hsa-miR-1269a

 

9.80E−04

0.086

−1.14

hsa-miR-4691-5p

 

8.60E−04

0.085

−1.15

hsa-miR-593-3p

 

1.39E−03

0.092

−1.16

hsa-miR-6767-3p

 

1.84E−03

0.099

−1.19

hsa-miR-3616-3p

 

7.10E−04

0.085

−1.20

hsa-miR-6833-3p

 

7.80E−04

0.085

−1.27

hsa-miR-3677-5p

 

1.38E−03

0.092

−1.28

hsa-miR-548s

 

2.50E−04

0.085

−1.29

hsa-miR-7706

 

1.40E−04

0.085

−1.29

hsa-miR-597-5p

hsa-miR-1970

1.43E−03

0.092

−1.29

hsa-miR-96-3p

 

4.50E−04

0.085

−1.31

hsa-miR-6828-5p

 

4.20E−04

0.085

−1.33

hsa-miR-372-5p

hsa-miR-295-5p

3.80E−04

0.085

−1.34

hsa-miR-3193

 

5.20E−04

0.085

−1.35

hsa-miR-6719-3p

 

5.60E−04

0.085

−1.37

hsa-miR-6814-3p

 

2.80E−04

0.085

−1.37

hsa-miR-5196-3p

 

1.20E−04

0.085

−1.38

hsa-miR-6742-3p

 

3.90E−04

0.085

−1.45

hsa-miR-4453

 

6.70E−04

0.085

−1.47

  1. miR ID, 39 Homo sapiens micro RNA species were discovered after statistical analysis of the data received from quantitative nuclease protection assay with the HTG EdgeSeq array system. IPA ID of miR Family Representatives, refer to miR IDs, where IPA assigns different micro RNA species representing the same micro RNA family, defined by an identical 7nt seed/ consensus sequence
  2. FDR false discovery rate values, samples with FDR values smaller 0.1 were considered as biological significant, LOG log 2 fold change of differential expression between deep nevi, which were considered similar to normal tissue versus superficial nevi, which were considered similar to atypical tissue
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