Fig. 1
From: hTERT promoter mutations in chondrosarcomas associate with progression and disease-related mortality
Chromatograms of the wild-type (top) hTERT promoter, and two examples (middle and lower) of the −124 C > T mutations found in chondrosarcomas. The amplitudes of the mutation curves indicate either contamination with normal DNA or a genetic subclone in the chondrosarcoma. Sequencing of punch biopsies from higher-grade tumor areas showed equivalent peak amplitude for the mutated and wild-type alleles (not shown)
