Fig. 8 | Modern Pathology

Fig. 8

From: Role of columnar cell lesions in breast carcinogenesis: analysis of chromosome 16 copy number changes by multiplex ligation-dependent probe amplification

Fig. 8

Trends in copy number changes in low-grade breast carcinogenetic spectrum. a Increasing frequency of 16q losses over the low-grade breast carcinogenetic spectrum. b Increasing frequency of 16q whole-arm loss over the low-grade breast carcinogenetic spectrum. c No trend of increasing 16p gains over the low-grade breast carcinogenetic spectrum. ADH, atypical ductal hyperplasia; BDA, blunt duct adenosis; CCL−, columnar cell lesion without atypia; CCL+, columnar cell lesion with atypia; DCIS, ductal carcinoma in situ; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; LN, lobular neoplasia; TubCa, tubular carcinoma; UDH, usual ductal hyperplasia

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